Explained: A recap of emerging evidence on Omicron
The Hindu
Its rapid spread is likely to test public health systems and their ability to react efficiently
It has been two weeks since the World Health Organization (WHO) designated Omicron as a Variant of Concern (VOC) in the ongoing SARS-Cov-2 coronavirus pandemic. Efforts by researchers from Africa and across the world over this time have provided immense insights into the epidemiology as well as biological properties of the virus. We provide a brief overview of the current understanding on the Omicron variant.
The earliest genome for what is now designated as the Omicron variant was sequenced from a viral isolate collected from Gauteng, South Africa in early November, 2021 and was made publicly available by the National Institute for Communicable Diseases, South Africa through GISAID, a database for sharing genomes of viruses. Further analysis revealed similar genomes deposited from Botswana and Hong Kong, characterised by a large number of mutations, particularly in the spike protein. This led researchers to report the cluster of genomes on the Pango Network, an open community of researchers working together to annotate lineages of SARS-CoV-2, and the lineage was thus designated as B.1.1.529.

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