Can autoantibodies play into coronavirus severity, long COVID? Some researchers suggest yes
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New findings out from Yale University suggest autoantibodies — or proteins acting against a person’s own tissues and organs — may correlate with COVID-19 severity and lasting symptoms.
"It's a two-edge sword," said Aaron Ring, assistant professor of immunobiology at Yale and senior author of the paper, in a news release posted to EurekAlert. "Antibodies are crucial to fend off infection, but some COVID-19 patients also develop antibodies that damage their own cells and tissues." In most cases, the coronavirus infection spurred the creation of autoantibodies, Ring said. But it’s possible some patients had pre-existing autoantibodies that heightened their vulnerability to infection which was confirmed through studies in mice, per the release.
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