Antimalarial vaccine–drug combo proves most efficacious in Africa trial
The Hindu
When the first malarial vaccine (named RTS,S) was used along with drugs, the efficacy went up to 70%, or more
When the World Health Organization’s Strategic Advisory Group of Experts on Immunisation (SAGE) considers, on October 6, evidence to decide on the roll out of the first malarial vaccine (RTS,S), the latest body of research – testing a vaccine combination with antimalarial drugs which demonstrated efficacy in preventing hospitalisations from severe malaria and deaths – is likely to bolster the case for voting aye. According to a paper recently published in the New England Journal of Medicine, the study measured the efficacy of vaccination with or without chemoprevention (drugs). The authors noted: “The combination of these interventions resulted in a substantially lower incidence of uncomplicated malaria, severe malaria, and death from malaria than either intervention alone.”
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