Primary Country (Mandatory)

United States

Other Country (Optional)

Set News Language for United States

Primary Language (Mandatory)
English
Other Language[s] (Optional)
No other language available

Set News Language for World

Primary Language (Mandatory)
English
Other Language(s) (Optional)

Set News Source for United States

Primary Source (Mandatory)
CNN
Other Source[s] (Optional)

Set News Source for World

Primary Source (Mandatory)
AajTak
Other Source(s) (Optional)
  • Countries
    • India
    • United States
    • Qatar
    • Germany
    • China
    • Canada
    • World
  • Categories
    • National
    • International
    • Business
    • Entertainment
    • Sports
    • Special
    • All Categories
  • Available Languages for United States
    • English
  • All Languages
    • English
    • Hindi
    • Arabic
    • German
    • Chinese
    • French
  • Sources
    • India
      • AajTak
      • NDTV India
      • The Hindu
      • India Today
      • Zee News
      • NDTV
      • BBC
      • The Wire
      • News18
      • News 24
      • The Quint
      • ABP News
      • Zee News
      • News 24
    • United States
      • CNN
      • Fox News
      • Al Jazeera
      • CBSN
      • NY Post
      • Voice of America
      • The New York Times
      • HuffPost
      • ABC News
      • Newsy
    • Qatar
      • Al Jazeera
      • Al Arab
      • The Peninsula
      • Gulf Times
      • Al Sharq
      • Qatar Tribune
      • Al Raya
      • Lusail
    • Germany
      • DW
      • ZDF
      • ProSieben
      • RTL
      • n-tv
      • Die Welt
      • Süddeutsche Zeitung
      • Frankfurter Rundschau
    • China
      • China Daily
      • BBC
      • The New York Times
      • Voice of America
      • Beijing Daily
      • The Epoch Times
      • Ta Kung Pao
      • Xinmin Evening News
    • Canada
      • CBC
      • Radio-Canada
      • CTV
      • TVA Nouvelles
      • Le Journal de Montréal
      • Global News
      • BNN Bloomberg
      • Métro
LN LENQIN Military Sport Watch Buy Now
Ascender Softshell Front-zip Jacket Buy Now
Embroidered Satin Shrug & Dhoti Set Buy Now
Multiport USB Charger for Multiple Devices Buy Now
Insignia Fire TV 32 inch Smart HD 720p Buy Now
HP Touchscreen Flagship Laptop for Business Buy Now
Polarized Aviator Sunglasses Buy Now
High-Waisted Workout Leggings Buy Now
Straight Leg Jeans for Women Buy Now
High-Waisted Chiffon A-Line Skirt Buy Now
ELEMIS Pro-Collagen Overnight Matrix Buy Now
Crystal Rhinestone Statement Necklace Buy Now
Mens Fashion Henley Shirt Classic Buy Now
Gildan Cotton T-Shirt Pack, Style G2000 Buy Now
Women's Trendy Summer Cap Sleeve Tees Buy Now
Wide Brim Straw Panama Hat Buy Now
Men's Linen Beach Shirt Buy Now
Business Casual Men Blazer Buy Now
Banarasi Silk Saree Buy Now
Striped Hawaiian Shirt Buy Now
LN LENQIN Military Sport Watch Buy Now
Ascender Softshell Front-zip Jacket Buy Now
Embroidered Satin Shrug & Dhoti Set Buy Now
Multiport USB Charger for Multiple Devices Buy Now
Insignia Fire TV 32 inch Smart HD 720p Buy Now
HP Touchscreen Flagship Laptop for Business Buy Now
Polarized Aviator Sunglasses Buy Now
High-Waisted Workout Leggings Buy Now
Straight Leg Jeans for Women Buy Now
High-Waisted Chiffon A-Line Skirt Buy Now
MoreBack to News Headlines
Unexpected link between nickel toxicity, cholesterol levels found
Premium

Unexpected link between nickel toxicity, cholesterol levels found Premium

The Hindu
Tuesday, November 5, 2024 12:38 AM GMT

Researchers from the University of Georgia discover a link between nickel exposure, sterol deficiency, and fungal growth in mammals.

Every so often, researchers discover a connection between what were believed to be completely unrelated phenomena. A team from the University of Georgia in the U.S. published one such report in the journal PLoS Genetics on September 16.  They discovered that exposing mammalian and fungal cells to the heavy metal nickel resulted in sterol deficiency.

Additionally, tolerance to nickel was found to increase when the fungal cells over-expressed a gene called ERG25, which encodes an enzyme. Cells unable to increase levels of the ERG25 enzyme were unable to grow in the presence of a higher nickel concentration.

Until this report, no one suspected nickel toxicity was related to sterol biosynthesis in fungi and animals.

Nickel was once used commonly to secure earrings in pierced ears, but it soon became clear that in a significant fraction of people it was a contact allergen. Nickel compounds are also known to be carcinogenic.

In the wild, on the other hand, plants, bacteria, and fungi need nickel for the normal function of an important enzyme called urease. For example, the fungus Cryptococcus neoformans uses urease to help it spread and colonise.

Sterols are an important chemical component of the cell membranes of plants, animals, and fungi. The compound makes the membranes more rigid.

In mammals including humans, the principal sterol is cholesterol. If it is present in high concentrations in the body, it tends to be deposited in the inner lining of our blood vessels. As the deposits accumulate, they block the flow of blood, eventually leading to chest pain, heart attack, and/or stroke.

Read full story on The Hindu
Share this story on:-
Run 3 Space | Play Space Running GamePlay Run 3, the ultimate space tunnel running game with 300+ challenging levels!Adv.
Traffic Jam 3D | Online Racing GameTraffic Jam 3D is a game where you’ll be driving through heavy traffic.Adv.
Duck Hunt | Play Old Classic GamePlay the classic 1984 light gun shooter game Duck Hunt on your browser.Adv.
More Related News
Learn to dive at Kathadi North in Rameswaram and explore Palk Bay’s marine life

Kathadi North: Boutique hotel in Rameswaram offering adventure sports, environmental conservation, and homely comfort by the sea.

Telescopes spot start of planet formation in Orion Premium

New study in Nature reveals first evidence of solid matter condensing from rock vapor around a star.

For hill-loving Bengal travellers, Uttarakhand is the flavour of the season

Seasoned travellers from Bengal seek spiritualism and sightseeing in Uttarakhand during monsoon, embracing lush landscapes and religious events.

NASA-ISRO Synthetic Aperture Radar satellite to be launched on July 30: ISRO

NISAR, a joint NASA-ISRO satellite, will launch on July 30 to observe Earth with advanced SAR technology.

Mental fatigue can trick the brain into taking the easy way out Premium

Study shows cognitive fatigue influences decision-making, favoring easier tasks over harder ones, impacting performance and focus.

Scientists document new snake locomotion in yellow anacondas

Breakthrough discovery of S-start motion in newborn yellow anacondas opens new avenues in snake evolution and soft-bodied robot design.

Meet Kerala’s growing community of women in motorsports

Women off-roaders in Kerala defy stereotypes, navigate obstacles, and compete in male-dominated motorsports with passion and skill.

The 7th edition of Shefs at The Leela celebrates women in culinary leadership

The Leela Palace Chennai presents the seven edition of Shefs at The Leela in collaboration with ‘Dean With Us’ — the mother-daughter duo of Rupali and Akansha Dean. The event honours the transformative role of Indian women chefs who are shaping the future of gastronomy. After past editions hosted across Bengaluru, Gurugram, Chennai, and Jaipur, the seventh edition in Chennai will bring together four women chefs — Sambhavi Joshi, Taiyaba Ali, Sehaj Ghuman and Bunuma Patagiri, who will bring their years of expertise into curating a menu that speaks both of their work and India’s diverse culinary heritage.  

Can Ozempic and other GLP-1 drugs be substitute for work outs? Dr Ambrish Mithal and Raj Ganpath discuss

Endocrinologist Dr Ambrish Mithal, the author of the recently-released book, The Weight Loss Revolution, talks to fitness and nutrition coach, Raj Ganpath, co-founder of The Quad, to decode GLP-1 drugs. Should you take them?

‘Desi Oon’ and Suresh Eriyat’s dialogue with shepherds

Filmmaker Suresh Eriyat’s award-winning stop-motion animation Desi Oon is a tactile masterpiece in storytelling and a reminder to look to artisans as equals

Pattu, the Doberman rescued in Chennai, finds forever home 7,200 km away in Prague

Rescued and brought to Besant Memorial Animal Dispensary in Besant Nagar, in a state of malnourishment and paralysis, Pattu the Doberman now lives it up in the Czech Republic

What is the universe’s antimatter mystery? | Explained Premium

Scientists discover CP violation in baryon decays, shedding light on why the universe is mostly made of matter.

Shubhanshu Shukla undergoing rehabilitation to mitigate any adverse effect of microgravity: ISRO

Indian astronaut Group Captain Shubhanshu Shukla undergoes rehabilitation post-space mission to counter microgravity effects, monitored by ISRO and Axiom.

Parking Slot | Free Parking GamePlay Parking Slot, the best online 3D car driving and parking game.Adv.
Slope Ball Run - Play OnlineSlope Game takes you on an exciting journey of a ball on special paths.Adv.
The virtues of the tomato, a healthy vegetable Premium

The fascinating evolution of tomatoes from "poison apples" to a beloved ingredient rich in health benefits worldwide.

Consistent effort key to India’s growth in space technology, says ISRO chairman

India has made great strides in space technology and attained global leadership through sheer hard work and consistent effort, V. Narayanan, Secretary, Department of Space, and Chairman, Indian Space Research Organisation (ISRO), said in Tiruchi on Saturday.

Why fashion education needs a makeover

Fashion education: Key areas for students include AI integration, skill development, ethical fashion, sustainability, and curriculum remodeling for industry success.

Efforts to restore mangroves can turn the tide on India’s coastal security Premium

Protecting India's mangroves is crucial for climate resilience, biodiversity, and coastal communities, with inspiring restoration efforts underway.

Home library space: a bibliophile’s dream

Creating a literary haven at home with cozy reading nooks, functional storage, and personal touches for bibliophiles.

Small home, big impact: the power of 500 sq.ft.

Empowering social shifts inspire architects to design affordable, well-ventilated, and climate-responsive studio apartments for urban youth.

Kia Carens Clavis EV review | It is the most accessible three-row electric MPV in the country

The Kia Carens Clavis EV marks a bold new chapter in India’s electric vehicle story — one that puts families first without pushing affordability to the back seat

Péro’s spring-summer capsule Flowers Flower, explores floral whimsy and legacy textiles

Péro has teamed up with British luxury brand Liberty London for its spring-summer 2025 capsule collection, Flowers Flower, that explores classic floral prints on legacy textiles

Science retracts NASA arsenic bacteria paper after years of controversy Premium

NASA's 2010 arsenic life claim, which the journal Science is finally retracting in 2025, highlights the complexities of scientific discovery and scrutiny.

Artist Vivi Jojo Vellukunnel’s water-inspired works will be showcased at an art party in Kumarakom

Experience Vivi Jojo Vellukunnel's abstract paintings inspired by water at 'The Mind of Water' art party in Kumarakom.

Understanding dictatorship and dictators: how did it all start?

Dictatorships are autocratic governments with little constraints, categorized as authoritarian, totalitarian, military, one-party, personalist, or monarchic.

Quiz: Easy like Sunday morning | All about proteins Premium

Madurai molecular biologist and quizmaster creating a rock ballad titled 'Coffee is a Drink, Kaapi is an Emotion'.

© 2008 - 2025 Webjosh  |  News Archive  |  Privacy Policy  |  Contact Us