Primary Country (Mandatory)

United States

Other Country (Optional)

Set News Language for United States

Primary Language (Mandatory)
English
Other Language[s] (Optional)
No other language available

Set News Language for World

Primary Language (Mandatory)
English
Other Language(s) (Optional)

Set News Source for United States

Primary Source (Mandatory)
CNN
Other Source[s] (Optional)

Set News Source for World

Primary Source (Mandatory)
AajTak
Other Source(s) (Optional)
  • Countries
    • India
    • United States
    • Qatar
    • Germany
    • China
    • Canada
    • World
  • Categories
    • National
    • International
    • Business
    • Entertainment
    • Sports
    • Special
    • All Categories
  • Available Languages for United States
    • English
  • All Languages
    • English
    • Hindi
    • Arabic
    • German
    • Chinese
    • French
  • Sources
    • India
      • AajTak
      • NDTV India
      • The Hindu
      • India Today
      • Zee News
      • NDTV
      • BBC
      • The Wire
      • News18
      • News 24
      • The Quint
      • ABP News
      • Zee News
      • News 24
    • United States
      • CNN
      • Fox News
      • Al Jazeera
      • CBSN
      • NY Post
      • Voice of America
      • The New York Times
      • HuffPost
      • ABC News
      • Newsy
    • Qatar
      • Al Jazeera
      • Al Arab
      • The Peninsula
      • Gulf Times
      • Al Sharq
      • Qatar Tribune
      • Al Raya
      • Lusail
    • Germany
      • DW
      • ZDF
      • ProSieben
      • RTL
      • n-tv
      • Die Welt
      • Süddeutsche Zeitung
      • Frankfurter Rundschau
    • China
      • China Daily
      • BBC
      • The New York Times
      • Voice of America
      • Beijing Daily
      • The Epoch Times
      • Ta Kung Pao
      • Xinmin Evening News
    • Canada
      • CBC
      • Radio-Canada
      • CTV
      • TVA Nouvelles
      • Le Journal de Montréal
      • Global News
      • BNN Bloomberg
      • Métro
Musey Yoga Tank Top Buy Now
Long Sleeve Sweater for Men Buy Now
COOFANDY Men's Wrinkle-Free Dress Shirt Buy Now
SHEWIN Womens Fashion Oversized T Shirts Buy Now
DUNLOP Waterproof PVC Boots Buy Now
Best Friend Keychain Gifts Buy Now
Longline Wirefree Sports Bra Buy Now
Roswear Women's Bermuda Shorts Buy Now
Beard Trimming Catcher Bib Buy Now
Women's Tote Bag: Work, Travel, Gym Buy Now
PELADN Mini PC Intel N5095 Buy Now
Beefy-T Heavyweight Cotton Tee Buy Now
HP Newest Flagship 15.6 HD Pavilion Laptop Buy Now
COOFANDY Men's Slim Fit Knit Sweater Buy Now
Turtleneck Long Sleeve Cable Knit Sweaters Buy Now
T-Shirt Beefy-T Heavyweight Buy Now
COOFANDY Men's Linen Shirts Buy Now
Rdruko Men's Track Suits Buy Now
Men's Casual Blazer Buy Now
Ninja BL770 Mega Kitchen System Buy Now
MoreBack to News Headlines
Tools to design proteins, predict structure win 2024 chemistry Nobel | Explained
Premium

Tools to design proteins, predict structure win 2024 chemistry Nobel | Explained Premium

The Hindu
Wednesday, October 9, 2024 4:44 PM GMT

Nobel Prize in Chemistry: he arrangement of amino acids relative to one another determines which function a particular protein will serve. Which is why, understanding the shapes of proteins is the key to understanding how life works.

The story so far: The 2024 Nobel Prize for chemistry was jointly awarded to David Baker for his research in the field of computational protein design and to Demis Hassabis and John M. Jumper for their work in protein structure prediction. The Swedish Academy of Royal Sciences announced the winners on October 9.

The chemistry prize concerns two areas in the field of protein research: design and structure.

All life (as we know it) requires proteins and all proteins are made of amino acids. While there are many types of amino acids in nature, only 20 of them in different combinations make up all the proteins in the human body and in most life-forms.

Amino acids are found in tissues — like muscles, skin, hair — that provide structural support, serve as catalysts for biochemical reactions, transport molecules like oxygen across biological membranes, control muscle contraction which lets us move and walk and makes our heart beat, and regulate cell communication that allow different functions to occur efficiently.

The arrangement of amino acids relative to one another determines which function a particular protein will serve. Understanding the 3D shapes of proteins is thus key. Scientists have spent decades trying to decode this. In 1962, University of Cambridge researchers John Kendrew and Max Perutz won the chemistry Nobel Prize for elucidating the first 3D models of haemoglobin and myoglobin (both proteins) using X-ray crystallography. In 1961, Christian Anfinsen found that a protein’s 3D structure is governed by the sequence of amino acids in the protein, and he won the 1972 chemistry prize.

One notable breakthrough arrived in 1969, when scientists found that a protein doesn’t try to bend into different shapes before settling into its final one. Instead it somehow knows the shape it needs to get to and gets there very quickly. The mysterious nature of this ‘knowledge’ of the protein is called the protein-folding problem.

By the late 2010s, scientists had worked out the structures of around 1.7 lakh proteins — a large number yet still small compared to the roughly 200 million proteins in nature. This situation changed drastically around 2018.

Read full story on The Hindu
Share this story on:-
Run 3 Space | Play Space Running GamePlay Run 3, the ultimate space tunnel running game with 300+ challenging levels!Adv.
Traffic Jam 3D | Online Racing GameTraffic Jam 3D is a game where you’ll be driving through heavy traffic.Adv.
Duck Hunt | Play Old Classic GamePlay the classic 1984 light gun shooter game Duck Hunt on your browser.Adv.
More Related News
Telescopes spot start of planet formation in Orion Premium

New study in Nature reveals first evidence of solid matter condensing from rock vapor around a star.

For hill-loving Bengal travellers, Uttarakhand is the flavour of the season

Seasoned travellers from Bengal seek spiritualism and sightseeing in Uttarakhand during monsoon, embracing lush landscapes and religious events.

NASA-ISRO Synthetic Aperture Radar satellite to be launched on July 30: ISRO

NISAR, a joint NASA-ISRO satellite, will launch on July 30 to observe Earth with advanced SAR technology.

Mental fatigue can trick the brain into taking the easy way out Premium

Study shows cognitive fatigue influences decision-making, favoring easier tasks over harder ones, impacting performance and focus.

Scientists document new snake locomotion in yellow anacondas

Breakthrough discovery of S-start motion in newborn yellow anacondas opens new avenues in snake evolution and soft-bodied robot design.

Meet Kerala’s growing community of women in motorsports

Women off-roaders in Kerala defy stereotypes, navigate obstacles, and compete in male-dominated motorsports with passion and skill.

The 7th edition of Shefs at The Leela celebrates women in culinary leadership

The Leela Palace Chennai presents the seven edition of Shefs at The Leela in collaboration with ‘Dean With Us’ — the mother-daughter duo of Rupali and Akansha Dean. The event honours the transformative role of Indian women chefs who are shaping the future of gastronomy. After past editions hosted across Bengaluru, Gurugram, Chennai, and Jaipur, the seventh edition in Chennai will bring together four women chefs — Sambhavi Joshi, Taiyaba Ali, Sehaj Ghuman and Bunuma Patagiri, who will bring their years of expertise into curating a menu that speaks both of their work and India’s diverse culinary heritage.  

Can Ozempic and other GLP-1 drugs be substitute for work outs? Dr Ambrish Mithal and Raj Ganpath discuss

Endocrinologist Dr Ambrish Mithal, the author of the recently-released book, The Weight Loss Revolution, talks to fitness and nutrition coach, Raj Ganpath, co-founder of The Quad, to decode GLP-1 drugs. Should you take them?

‘Desi Oon’ and Suresh Eriyat’s dialogue with shepherds

Filmmaker Suresh Eriyat’s award-winning stop-motion animation Desi Oon is a tactile masterpiece in storytelling and a reminder to look to artisans as equals

Pattu, the Doberman rescued in Chennai, finds forever home 7,200 km away in Prague

Rescued and brought to Besant Memorial Animal Dispensary in Besant Nagar, in a state of malnourishment and paralysis, Pattu the Doberman now lives it up in the Czech Republic

What is the universe’s antimatter mystery? | Explained Premium

Scientists discover CP violation in baryon decays, shedding light on why the universe is mostly made of matter.

Shubhanshu Shukla undergoing rehabilitation to mitigate any adverse effect of microgravity: ISRO

Indian astronaut Group Captain Shubhanshu Shukla undergoes rehabilitation post-space mission to counter microgravity effects, monitored by ISRO and Axiom.

Gujarat launches India’s first tribal genome project to tackle inherited diseases

Gujarat launches genome sequencing project for tribal communities to identify genetic health risks and enable precision healthcare.

Parking Slot | Free Parking GamePlay Parking Slot, the best online 3D car driving and parking game.Adv.
Slope Ball Run - Play OnlineSlope Game takes you on an exciting journey of a ball on special paths.Adv.
Consistent effort key to India’s growth in space technology, says ISRO chairman

India has made great strides in space technology and attained global leadership through sheer hard work and consistent effort, V. Narayanan, Secretary, Department of Space, and Chairman, Indian Space Research Organisation (ISRO), said in Tiruchi on Saturday.

Why fashion education needs a makeover

Fashion education: Key areas for students include AI integration, skill development, ethical fashion, sustainability, and curriculum remodeling for industry success.

Efforts to restore mangroves can turn the tide on India’s coastal security Premium

Protecting India's mangroves is crucial for climate resilience, biodiversity, and coastal communities, with inspiring restoration efforts underway.

Home library space: a bibliophile’s dream

Creating a literary haven at home with cozy reading nooks, functional storage, and personal touches for bibliophiles.

Small home, big impact: the power of 500 sq.ft.

Empowering social shifts inspire architects to design affordable, well-ventilated, and climate-responsive studio apartments for urban youth.

Kia Carens Clavis EV review | It is the most accessible three-row electric MPV in the country

The Kia Carens Clavis EV marks a bold new chapter in India’s electric vehicle story — one that puts families first without pushing affordability to the back seat

Péro’s spring-summer capsule Flowers Flower, explores floral whimsy and legacy textiles

Péro has teamed up with British luxury brand Liberty London for its spring-summer 2025 capsule collection, Flowers Flower, that explores classic floral prints on legacy textiles

Science retracts NASA arsenic bacteria paper after years of controversy Premium

NASA's 2010 arsenic life claim, which the journal Science is finally retracting in 2025, highlights the complexities of scientific discovery and scrutiny.

Artist Vivi Jojo Vellukunnel’s water-inspired works will be showcased at an art party in Kumarakom

Experience Vivi Jojo Vellukunnel's abstract paintings inspired by water at 'The Mind of Water' art party in Kumarakom.

Understanding dictatorship and dictators: how did it all start?

Dictatorships are autocratic governments with little constraints, categorized as authoritarian, totalitarian, military, one-party, personalist, or monarchic.

Quiz: Easy like Sunday morning | All about proteins Premium

Madurai molecular biologist and quizmaster creating a rock ballad titled 'Coffee is a Drink, Kaapi is an Emotion'.

Learn to dive at Kathadi North in Rameswaram and explore Palk Bay’s marine life

Kathadi North: Boutique hotel in Rameswaram offering adventure sports, environmental conservation, and homely comfort by the sea.

© 2008 - 2025 Webjosh  |  News Archive  |  Privacy Policy  |  Contact Us