Primary Country (Mandatory)

United States

Other Country (Optional)

Set News Language for United States

Primary Language (Mandatory)
English
Other Language[s] (Optional)
No other language available

Set News Language for World

Primary Language (Mandatory)
English
Other Language(s) (Optional)

Set News Source for United States

Primary Source (Mandatory)
CNN
Other Source[s] (Optional)

Set News Source for World

Primary Source (Mandatory)
AajTak
Other Source(s) (Optional)
  • Countries
    • India
    • United States
    • Qatar
    • Germany
    • China
    • Canada
    • World
  • Categories
    • National
    • International
    • Business
    • Entertainment
    • Sports
    • Special
    • All Categories
  • Available Languages for United States
    • English
  • All Languages
    • English
    • Hindi
    • Arabic
    • German
    • Chinese
    • French
  • Sources
    • India
      • AajTak
      • NDTV India
      • The Hindu
      • India Today
      • Zee News
      • NDTV
      • BBC
      • The Wire
      • News18
      • News 24
      • The Quint
      • ABP News
      • Zee News
      • News 24
    • United States
      • CNN
      • Fox News
      • Al Jazeera
      • CBSN
      • NY Post
      • Voice of America
      • The New York Times
      • HuffPost
      • ABC News
      • Newsy
    • Qatar
      • Al Jazeera
      • Al Arab
      • The Peninsula
      • Gulf Times
      • Al Sharq
      • Qatar Tribune
      • Al Raya
      • Lusail
    • Germany
      • DW
      • ZDF
      • ProSieben
      • RTL
      • n-tv
      • Die Welt
      • Süddeutsche Zeitung
      • Frankfurter Rundschau
    • China
      • China Daily
      • BBC
      • The New York Times
      • Voice of America
      • Beijing Daily
      • The Epoch Times
      • Ta Kung Pao
      • Xinmin Evening News
    • Canada
      • CBC
      • Radio-Canada
      • CTV
      • TVA Nouvelles
      • Le Journal de Montréal
      • Global News
      • BNN Bloomberg
      • Métro
Business Dress Shirts Wrinkle Free Buy Now
Straight Leg Jeans for Women Buy Now
Linen Wide Leg Pants Buy Now
Men's Knit Cardigan Buy Now
Into the AM Men's T-Shirt Buy Now
Womens Soft Satin Pajama Set Buy Now
Afterburn M. Fit Sneaker Buy Now
Men's Linen Casual Long Pants Buy Now
Men's Ecosmart Fleece Sweatshirt Buy Now
Smart Piano with Rainbow Lights Buy Now
SAMSUNG Galaxy S24 Ultra Cell Phone Buy Now
Swarovski Subtle Bracelet Buy Now
HD Sound Bluetooth Speaker Buy Now
Butterfly Fashion Sunglasses Buy Now
OptiPlex 7020 i5-14500T MFF Buy Now
OLOV Electric Body Hair Trimmer Buy Now
Multifunctional Cleaning Kit Buy Now
Mens Golf Pants Buy Now
Wacky Waving Inflatable Tube Guy Buy Now
4K Dual Screen Camera with 18X Zoom Buy Now
MoreBack to News Headlines
Organ-on-chip tech could boost BioE3 goal to personalise medicine
Premium

Organ-on-chip tech could boost BioE3 goal to personalise medicine Premium

The Hindu
Thursday, September 12, 2024 12:44 AM GMT

India's BioE3 policy aims to drive innovation in biotechnology, focusing on precision therapeutics and organ-on-chip technology.

On August 24, the Government of India announced the ‘BioE3’ policy to drive innovation in the biotechnology sector by establishing biomanufacturing facilities, bio-AI hubs, and bio-foundries. (‘AI’ stands for artificial intelligence.) A key focus area of the policy is precision therapeutics, which involve developing and administering drugs according to the needs of individual patients. The policy also aims to boost the development of biologics such as gene therapy and cell therapy.

Recent advancements in human-relevant 3D culture models, also known as ‘new approach methods’ (NAMs), have shown promising results in the field of precision therapeutics. These models include 3D spheroids, organoids, bioprinting, and organ-on-chips.

The global organ-on-chip market is expected to be worth around $1.4 billion by 2032. This expansion is the result of increasing investments in R&D within the field of NAMs, particularly in organ-on-a-chip technology. Since its invention, this technology has acquired significant momentum and stands poised to revolutionise the healthcare sector by integrating cells derived from a human body with a well-defined in vitro biological environment (i.e. in the lab) that mimics the body’s conditions.

A major driving factor in the organ-on-chip market is the increasing demand to replace the use of animals to test drugs.

In April, an English company named CN Bio raised $21 million from venture capitalists to expand its R&D in organ-on-chip technology. In the U.S., Vivodyne raised $38 million in seed funding to integrate large-scale automation and AI with organ-on-chips. These are just two recent examples to illustrate the growing interest in this technology and its commercial value.

In the current and traditional drug development process, researchers take almost a decade and an average cost of $2.3 billion to bring a new drug from the lab to the market. However, many drug candidates also fail in the final stages of clinical trials. One major reason is that in the early stages of trials, these drugs are tested on animal models — animals genetically engineered to respond to a drug the way a human organ (or organs) might. Drugs that succeed on these animals often fail in humans, however.

Organ-on-chip technology offers a potential solution to this problem by providing a more accurate and efficient platform for testing drugs without involving animals or humans in preclinical testing. An organ-on-chip is a small device designed to recreate the dynamic functions of some human organ in a controlled microenvironment. They are expected to be better than the cell cultures and animal models researchers currently use at testing the effects of a drug. The results from the use of these devices would in turn provide a better understanding of the drug-candidate’s efficacy and toxicity, reduce the use of animals, and pave the way for personalised treatment.

Read full story on The Hindu
Share this story on:-
Run 3 Space | Play Space Running GamePlay Run 3, the ultimate space tunnel running game with 300+ challenging levels!Adv.
Traffic Jam 3D | Online Racing GameTraffic Jam 3D is a game where you’ll be driving through heavy traffic.Adv.
Duck Hunt | Play Old Classic GamePlay the classic 1984 light gun shooter game Duck Hunt on your browser.Adv.
More Related News
VinFast’s India strategy will have an entire EV ecosystem, including strong dealership presence in Tier two and three cities

VinFast’s entry into India is a strategic one, and it comes with real investment. The company is setting up a manufacturing facility in Tuticorin, Tamil Nadu, with an initial capacity of 50,000 vehicles per year, scalable to 150,000 units annually. With an investment of up to USD 500 million, this is not a soft launch—it is a full-fledged push into what is one of the world’s most promising auto markets.

What is the origin of gravity? Premium

Isaac Newton and Albert Einstein's theories on gravity explained, from mass and distance to spacetime deformation and energy.

Why do we use QWERTY keyboards?

The history of the QWERTY keyboard layout and why it remains the standard despite more efficient alternatives available.

The story of how heeng came to be successfully cultivated in India Premium

Heeng, an essential ingredient in Indian cuisines, is successfully cultivated in India, reducing import dependence and enhancing farmer incomes.

Indian astronaut Shubhanshu Shukla’s mission to International Space Station postponed once again

ISRO postpones Axiom-4 mission launch to ISS for Indian astronaut due to weather conditions, rescheduled for June 11.

Picture of the week: The superhumans of Mumbai

In Mallakhamb, a traditional performative sport from India, performers balance themselves on a pole and perform acrobatics.

‘Magical’ new technique brings very dilute samples into focus Premium

New MagIC method allows cryo-EM study of rare molecules at 100x lower concentration, aided by DuSTER computer workflow.

Physics changed AI in the 20th century. Is AI returning the favour? Premium

Discover how AI is transforming scientific research, from predicting protein structures to advancing quantum technologies.

Using bacteriophages to combat antimicrobial resistance Premium

Discover the potential solution to antibiotic resistance with bacteriophages, a natural alternative to combat bacterial infections effectively.

One of the oldest unsolved problems

On June 7, 1742, Prussian mathematician Christian Goldbach wrote a letter to Swiss polymath Leonhard Euler. Why does it warrant attention, you seem to be asking. Goldbach outlined a conjecture that bears his name in this letter, a conjecture that is now one of the oldest and most famous unsolved problems in all of number theory. Intrigued? A.S.Ganesh hands you more details about Goldbach and Goldbach’s conjecture…

Design finds from Chennai

Discover artisanal lifestyle products at Jaypore, Suvasa, and Bagh in Chennai, offering handcrafted decor, dinnerware, and textiles.

The link between leprosy and climate-change that we did not know about: an Indian story Premium

Leprosy resurfaces in India due to climate change, poverty, and stigma, demanding urgent interventions and visibility.

Commercial real estate booming in non-metros

Amit Ramani of Awfis Space Solutions discusses the transformative growth trajectory of India's commercial real estate sector.

Parking Slot | Free Parking GamePlay Parking Slot, the best online 3D car driving and parking game.Adv.
Slope Ball Run - Play OnlineSlope Game takes you on an exciting journey of a ball on special paths.Adv.
Is psychology’s replication crisis behind us? Premium

New research shows psychology has improved standards post-replication crisis, with fewer fragile p-values and rising statistical power.

What the IAEA’s non-compliance resolution means for Iran, and the world Premium

IAEA declares Iran in breach of obligations, sparking global tensions over nuclear program and potential sanctions.

What the IAEA’s non-compliance resolution means for Iran, and the world Premium

IAEA declares Iran in breach of obligations, sparking global tensions over nuclear program and potential sanctions.

Science behind setting the right temperature on the air conditioner

Union Ministry of Power considers restricting new ACs to 20-28 degrees Celsius for energy efficiency and health benefits.

What made Boeing 787s popular – and later a cause for concern Premium

Air India flight AI171 crash details, Boeing 787-8 Dreamliner design, engine specifics, and safety concerns explained.

Waymo leads autonomous taxi race in the U.S.

Waymo’s autonomous vehicles have become part of the everyday landscape in a growing number of U.S. cities.

Pride Month 2025| Interfaith Pride Fest to be held in Hyderabad

Interfaith Pride Fest in Hyderabad on June 14 celebrates queerness and spirituality, offering a safe space for expression and reflection.

How safe AI is in healthcare depends on the humans of healthcare Premium

AI tools are quietly reshaping Indian healthcare. From foetal ultrasound dating and high-risk-pregnancy guidance to virtual autopsies and clinical chatbots, they are matching expert accuracy while accelerating workflows. Yet their promise comes entwined with the systemic challenges of data and automation bias, privacy, and weak regulation, often exacerbated by the sensitivities of the healthcare sector itself.

Kerala University’s archaeological excavation unearths 5,300-year-old Early Harappan settlement in Gujarat

University of Kerala archaeologists uncover 5,300-year-old Early Harappan settlement near Lakhapar village in Gujarat, revealing unique cultural insights.

Watch: A beginner’s guide to brewing coffee

Divya Jayashankar at Beachville Coffee Roasters takes us through a beginner-friendly guide to coffee brewing methods in Chennai.

Elon Musk says Tesla’s robotaxi service to “tentatively” launch in Austin on June 22

The Austin Tesla rollout also comes after Musk had a public blow-up with U.S. President Donald Trump over the administration’s tax bill.

Monsoon-loving Indian expats chase rain in UAE desert

Indian expat in UAE chases elusive rain in the desert, using high-tech tools to forecast and enjoy monsoon nostalgia.

© 2008 - 2025 Webjosh  |  News Archive  |  Privacy Policy  |  Contact Us