How Netflix's The Good Nurse flips the script on the true crime genre

The Good Nurse isn't your typical true crime story. The Netflix production, starring Jessica Chastain and Eddie Redmayne, tells the true story of Amy Loughren, a New Jersey nurse who learns her close friend and co-worker is a serial killer. 

Instead of focusing solely on troubled nurse and killer Charles Cullen, The Good Nurse chooses to highlight Loughren's bravery as she worked with police to bring Cullen down.

"One of the first things Amy said to me when I said, 'Thank you so much for everything you did, it was an incredible risk to yourself,' was, 'Anyone would have done what I would have done,'' Chastain told CBC News at the film's TIFF premiere in September.

Cullen, a nurse in the Intensive Care Unit along with Loughren, was convicted in 2006 for killing 29 people using fatal doses of intravenous medications, although he confessed to killing at least 40 and experts suspect it's possible that he could have caused more than 300 deaths until his arrest.

In 2003, Loughren wore a recording device to capture Cullen's confessions, which police later used to arrest him. 

WATCH | The Good Nurse cast describe Amy Loughren's heroic acts:

Loughren worked closely with Chastain, both over Zoom and on set, to capture Loughren's empathy and the nuance of her actions, she told CBC News.

"She really wanted to be fiercely compassionate, and I think that she does that," Loughren said of Chastain's performance.

Redmayne, who plays Cullen, said he hadn't heard about the killer before reading the script, and couldn't believe how the story unravelled.

"This man, who seemed very gentle, very kind, very empathetic, was using that empathy and weaponizing it to do horrific things," he told CBC News.

Noah Emmerich, who plays detective Tim Braun, said his role was different from other detectives he portrayed in the past. "The detectives couldn't get him. They were totally dead in the water until this little angel, Amy."

The film isn't the first adaptation of the murders. British channel Sky Crime ran a documentary called Charles Cullen — Killing for Kindness in 2020. Another 2008 film, Killer Nurse, was inspired by the serial killer. The Netflix movie is based on the 2013 novel The Good Nurse: A True Story of Medicine, Madness, and Murder by Charles Graeber.

WATCH | How friendship helped Jessica Chastain and Eddie Redmayne film gritty scenes:

It was a tough story to tell, Redmayne said, but working with Chastain helped. He noted he and Chastain had been friends for a number of years, but hadn't really gotten the chance to work together before The Good Nurse.