Everything old is new again: Repurposing drugs to treat Covid-19
CNN
The practice of finding new uses for old medications -- called repurposing or repositioning drugs -- is not new.
The most famous (or perhaps infamous) example is sildenafil -- aka: Viagra. Originally developed to treat high blood pressure, the little blue pill received US Food and Drug Administration approval in 1998 to treat erectile dysfunction, and very quickly became a blockbuster drug. Another notable example is thalidomide. Given to women in the late 1950s to prevent morning sickness -- and soon found to cause severe birth defects -- it got a second life in 1998 as treatment for leprosy (now called Hansen's disease), and then a third life in 2006, when it was approved to treat multiple myeloma, cancer of the bone marrow.
Colorado prosecutors on Friday argued additional charges against James Craig, a dentist accused of fatally poisoning his wife, as new details were revealed in court about how he allegedly tried to get a fellow inmate to kill a detective on the case.
One week into the Trump administration, Homeland Security Secretary Kristi Noem issued a directive that the Federal Emergency Management Agency should stop sending money to non-governmental organizations that she characterized as helping “illegal aliens.”
The morning after the mass resignation of prosecutors sparked a crisis inside the Trump Justice Department, acting Deputy Attorney General Emil Bove led a meeting with the Justice Department’s public integrity section. His message: they had to choose one career lawyer to file a dismissal of the corruption charges against New York City Mayor Eric Adams, according to three people briefed on the meeting.
Seventh prosecutor in Eric Adams case resigns and calls out Trump’s former lawyer in scathing letter
A federal prosecutor assigned to the corruption case against New York City Mayor Eric Adams resigned Friday in a blistering letter that accused top leaders at the Justice Department of looking for a “fool” to dismiss the criminal charges.
A Texas judge on Thursday ordered a New York doctor to pay more than $100,000 in penalties for prescribing abortion pills to a woman near Dallas, a ruling that could test “shield laws” in Democratic-controlled states where abortion is legal.
The Trump administration has gutted the federal government’s ability to fight public corruption in a matter of weeks.
A woman suspected of killing three members of the same family by poisoning a Christmas cake has been found dead in her prison cell in Brazil.
An Indiana teenager has been accused of plotting a school shooting on Valentine’s Day allegedly inspired by the gunman who murdered 17 people at a Parkland, Florida, high school on February 14, 2018, according to police and court records.
Vice President JD Vance warned on Thursday that the United States could send troops to Ukraine and hit Russia with further sanctions if Vladimir Putin doesn’t negotiate a peace deal in good faith.
After accruing immense governmental power over the past month, tech billionaire Elon Musk got his biggest boost yet this week when President Donald Trump signed an executive order giving him broad authorities over the hiring and firing of federal workers.
Border czar Tom Homan met with New York City Mayor Eric Adams on Thursday in a sign of how the Trump administration has its eyes on the country’s biggest city to carry out its immigration enforcement plans.
The National Park Service has removed references to transgender and queer people on its web page for the Stonewall National Monument, which marks the site of the New York City inn where LGBTQ rioters – including now-legendary transgender activists – galvanized a movement for LGBTQ rights.
The Trump administration broadened its effort to terminate thousands of probationary workers on Thursday, instructing agencies on a call to move forward with the layoffs.