A new drug shows promise against respiratory virus, study shows
CNN
A new antiviral medication against respiratory syncytial virus, or RSV, appears to be safe and lowered viral levels and symptoms significantly more than a placebo, according to the results of a study published Wednesday in The New England Journal of Medicine.
The study is unusual in that it is based on a two-part human challenge trial, where researchers purposefully infect people with a pathogen to test a new therapy. Challenge studies speed up research because scientists don't have to wait for their study participants to get sick out in the real world. They can also enroll fewer people, knowing that participants will inevitably catch a germ. But they're also risky and only considered ethical when the need for a new treatment or therapy is thought to outweigh the potential risks to study participants.
A winter virus that inundates pediatricians
Rescuers are searching for a missing Pennsylvania grandmother who is believed to have fallen deep into a sinkhole while searching for her cat with her young granddaughter, authorities said.
Elon Musk and Vivek Ramaswamy are suggesting the country stop its biannual ritual of falling back and springing forward – advocating a permanent end to time changes in a move that has garnered broad support in the past.
A woman who flew as a stowaway on a Delta Air Lines flight from New York to Paris earlier this week remains in France after causing a disturbance on a flight scheduled to take her back to the United States Saturday, according to two law enforcement sources.
Donald Trump’s choice of Pete Hegseth to run the Defense Department is in jeopardy amid questions from some key GOP senators over whether he’s fit for the job, forcing the president-elect’s team to maneuver behind the scenes to avoid a second Cabinet pick from collapsing amid a Republican revolt.
Kash Patel, President-elect Donald Trump’s pick to run the FBI, was recently informed by the bureau that he had been targeted as part of an Iranian hack, two sources familiar with the matter told CNN.
Chad Chronister, a Florida sheriff, has withdrawn from consideration as President-elect Donald Trump’s pick to lead the Drug Enforcement Administration, he announced on Tuesday.
Defense lawyers for President-elect Donald Trump are using President Joe Biden’s pardon of his son Hunter to argue that Trump’s conviction in his Manhattan hush money case should be dismissed.
Donald Trump’s transition team has signed a Memorandum of Understanding with the Justice Department, paving the way for the team to seek FBI background checks on the president-elect’s appointees.
A California man who allegedly confessed to helping the North Korean regime prepare for an attack on South Korea was arrested by the FBI on Tuesday in what federal investigators described as a “sophisticated scheme” to illegally obtain restricted weapons and military grade technology.
The Supreme Court will dive headfirst into the politically fraught issue of transgender rights on Wednesday when it hears a challenge to Tennessee’s ban on gender-affirming care for minors in the highest-profile case of the fall.
Supreme Court majority appears skeptical of allowing Holocaust survivors to sue Hungary in US courts
A majority of the Supreme Court on Tuesday appeared skeptical that Holocaust victims and their families are permitted to haul Hungary into American courts to recover property stolen during World War II, with several justices fearing that would open the United States up to a flood of similar litigation from abroad.