双语早读丨世界首个“牙齿再生药物”将在日本进行临床试验
China Daily
据日本媒体报道,日本科学家将开展世界首个“牙齿再生药物”的临床试验,研究人员希望这种药物不仅能治疗先天缺牙症,最终还可以帮助后天缺牙和蛀牙患者长出新牙。
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据日本《每日新闻》报道,日本科学家将在京都大学医学部附属医院开展世界上首个“牙齿再生药物”的临床试验。
Japanese scientists are set to kick off the world's first clinical trials of "tooth regrowth medicine" at the Kyoto University Hospital, The Mainichi reports.
来自日本初创公司Toregem Biopharma的研究人员计划招募一批从出生起就缺少部分或全部牙齿(先天缺牙症)的患者参加这次试验。
Researchers from the Japanese startup Toregem Biopharma are planning to enroll patients who were born missing some or all of their teeth from birth, a condition called congenital anodontia, for the trials.
患者将接受一种抗体治疗,这种治疗可以阻断一种名为USAG-1的蛋白质,科学家认为这种蛋白质阻止了大多数人的牙蕾发育成乳牙或恒牙。
The patients will receive an antibody treatment that deactivates a protein called USAG-1, believed to stop "tooth buds," which most people have, from developing into either baby or permanent teeth.
患有先天缺牙症的人通常选择种植牙或假牙。然而,正如《日经亚洲》援引Toregem公司共同创始人高桥克的声明所提到的,治疗可能将为他们提供“第三种选择”。
People with the condition conventionally resort to getting implants or dentures. However, Toregem's treatment could provide them with a "third option," as co-founder Katsu Takahashi explained in a statement, as quoted by Nikkei Asia.
研究团队希望不仅能治疗那些从出生起就无法长出牙齿的人,最终还能治疗那些因蛀牙而缺失牙齿的人。