Christina Applegate Opens Up About 'Fatalistic' Depression: 'I Don't Enjoy Living'

The "Dead to Me" star, who was diagnosed with multiple sclerosis in 2021, said on her podcast that the "darkness" she's been living in is "scaring" her.

Christina Applegate, who has openly discussed her diagnosis of multiple sclerosis before, is now detailing the deep depression she’s experiencing as she navigates the disease’s symptoms.

“I am in a depression right now, which I don’t think I’ve felt for years,” the “Dead to Me” star told her “MeSsy” podcast co-host Jamie-Lynn Sigler on Tuesday’s episode. “Like, a real ‘fuck it all’ depression ... where it’s kind of scaring me too, a little bit, because it feels really fatalistic.”

“It feels really ‘end of it,’” Applegate continued. “I don’t mean that, I just mean I’m trapped in this darkness right now that I haven’t felt in, like, I don’t even know how long, probably 20-something years.”

In the conversation, which was recorded earlier this year, Applegate confirmed having called a therapist to discuss those feelings. She noted that even making an appointment, however, was a “big thing” for her.

“I have avoided therapy since I’ve been diagnosed because I’m so afraid to start crying and that I’m not going to be able to end crying,” the 52-year-old told Sigler. “And so my way of doing things is to make fun of myself … [like] at that stage [at the Emmys in January].”